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Lastly using SSDE for size adjustment would not account for the differences in patient case mix across hospitals

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To study further the potential mechanisms underlying these associations, we conducted a pathway analysis of DON exposure on polar metabolites within both control and case groups

Blood 280a, 1999

Interestingly, a recent research described a new mechanism by which selenomethione protects cardiomyocytes from doxorubicin-induced ferroptosis through activating GPX4 [101]